USAGE OF TOLUIDINE BLUE IN EARLY DETECTION OF MALIGNANT AND PREMALIGNANT LESIONS

Authors

  • Tariq Khan Department of Oral & Maxillofacial Surgery, Saidu Group of Teaching Hospitals, Swat
  • Shams ul Alam Catogary D Hospital, Health Department, District, Shangla
  • Muhammad Aamir Department of Oral & Maxillofacial Surgery, Gajju Khan Medical College, Swabi
  • Sultan Zeb Department of Oral Pathology, Khyber College Of Dentistry, Peshawar
  • Mehwish Waris Department of Oral Pathology, KMU Institute Of Dental Sciences, Kohat
  • Umar Hussain Catogary D Hospital, Health Department, District, Shangla
  • Asmat Ullah Department of Oral Medicine, Khyber College of Dentistry, Peshawar ABSTRACT

DOI:

https://doi.org/10.33279/jkcd.v10i02.319

Keywords:

Toluidine Blue, Histopathology, Blue staini

Abstract

Objective: To Test the utility of toluidine blue staining in the early diagnosis of malignant and premalignant lesions.

Materials and Methods: This was a Randomized control clinical trial, carried out at Oral and Maxillofacial Department Gajju Khan Medical College, Bacha Khan Medical Complex, Swabi from 15th April 2019 to 15th April 2020. Twenty two patients with the clinical suspicious lesions were selected. Oral rise was done with 1% acetic acid and later Toluidine blue (1%W/W) was applied with sterile swab stick. Again oral rise was done with normal saline. Colour of the lesion was noted. Later incisional biopsy was taken as gold standard.

Results: Total of 22 cases the males were 14(63.6%) and females were 8(36.4%). The sensitivity and specificity of toluidine blue against gold standard of histopathology were 88.89% and 61.54% % respectively. The diagnostic accuracy of toluidine blue was 72.73%.

Conclusion: Toluidine blue is very good, effective and simple staining procedure. The staining method is more tolerable by the patient. It may help not only in detecting early dysplastic and malignant lesions but will also help in determining the site of biopsy to be taken.

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Published

2020-06-30

How to Cite

Tariq Khan, Shams ul Alam, Muhammad Aamir, Sultan Zeb, Mehwish Waris, Umar Hussain, & Asmat Ullah. (2020). USAGE OF TOLUIDINE BLUE IN EARLY DETECTION OF MALIGNANT AND PREMALIGNANT LESIONS. JOURNAL OF KHYBER COLLEGE OF DENTISTRY, 10(02), 55–58. https://doi.org/10.33279/jkcd.v10i02.319

Issue

Vol. 10 No. 02 (2020): Journal of Khyber College of Dentistry

Section

Original Article

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Copyright (c) 2020 Tariq Khan, Shams ul Alam, Muhammad Aamir, Sultan Zeb, Mehwish Waris, Umar Hussain, Asmat Ullah

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