CLINICO-PATHOLOGICAL FEATURES OF ORAL SQUAMOUS CELL CARCINOMA AMONG TOBACCO USERS AND NON-TOBACCO USERS

Authors

  • Sana Ahmad Department of Oral Pathology, Bacha Khan Dental College.
  • Abbas Saleem Khan Department of Oral Pathology, Peshawar Dental College, Riphah International University.
  • Muhammad Nisar Department of Oral Pathology, Peshawar Dental College, Riphah International University.
  • Syed Umer Farooq Department of Oral Pathology, Kohat Institute of Dental Sciences, Khyber Medical University.
  • Syed Muhammad Awais Department of Dental Materials, Bacha Khan Dental College.
  • Muazzam Ahmad Department of Pharmacology, Khyber Medical College.
  • Sajjad Ahmad Department of Pathology, Peshawar Medical College, Riphah International University.
  • Muhammad Umar Farooq OMFS, Dental Department, Pakistan Institute of Medical Sciences, SZAB Medical University.
  • Muhammad Rauf Khattak Institute of Radiotherapy and Nuclear Medicine, University campus, Peshawar.
  • Shuja Riaz Ansari Department of Oral and Maxillofacial Surgery, Khyber College of Dentistry Peshawar.

DOI:

https://doi.org/10.33279/jkcd.v8i4.562

Keywords:

Oral Squamous Cell Carcinoma, Tobacco, Grading and TNM staging

Abstract

Objectives:To assess the clinicopathological features of oral squamous cell carcinoma (OSCC) cases among tobacco users and non -users.
Materials & Methods:This cross-sectional study was conducted at various departments of oral and maxillofacial surgery [BKDC, KCD, PDC, KIDS, PIMS] and IRNUM on 140 cases of OSCC from March 2103 to September 2017. OSCC cases were randomly selected by adopting a convenient sampling technique. Histopathologically diagnosed cases of OSCC with and without a history of tobacco products use were included. Data regarding age, gender, primary anatomical site of a tumour and details about the type and pattern of tobacco products use were recorded, evaluated and analyzed by SPSS version 20.
Results:The mean age recorded for OSCC patients was 53.03 years with a male to female ratio of 1.5:1. The least commonly affected site was a lip (3%). The most commonly occurring histopathological grades among tobacco users and non-users were well differentiated squamous cell carcinoma (WDSCC) and moderately differentiated squamous cell carcinoma (MDSCC) respectively. Majority of cases presented in stage III (46%), followed by stage IV (25%), stage II (21%) and stage I (8%).
Conclusion:The study observes a high frequency of male tobacco user patients, aged 40 years and above. PDSCC was the least commonly observed histopathological grade among tobacco users and non-users. Most commonly affected sites of development for OSCC were cheek mucosa, retromolar area and vestibule of mouth and mostly the patients reported in the late stage (III) of
oral malignancy.

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Published

2018-12-31

How to Cite

Sana Ahmad, Abbas Saleem Khan, Muhammad Nisar, Syed Umer Farooq, Syed Muhammad Awais, Muazzam Ahmad, Sajjad Ahmad, Muhammad Umar Farooq, Muhammad Rauf Khattak, & Shuja Riaz Ansari. (2018). CLINICO-PATHOLOGICAL FEATURES OF ORAL SQUAMOUS CELL CARCINOMA AMONG TOBACCO USERS AND NON-TOBACCO USERS . JOURNAL OF KHYBER COLLEGE OF DENTISTRY, 8(4), 8–14. https://doi.org/10.33279/jkcd.v8i4.562

Issue

Vol. 8 No. 4 (2018): Journal of Khyber College of Dentistry

Section

Original Article

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Copyright (c) 2018 Sana Ahmad, Abbas Saleem Khan, Muhammad Nisar, Syed Umer Farooq, Syed Muhammad Awais, Muazzam Ahmad, Sajjad Ahmad, Muhammad Umar Farooq, Muhammad Rauf Khattak, Shuja Riaz Ansari

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