ROLE OF ANTIBIOTICS IN CONTROL OF POST-ENDODONTIC PAIN: CASES OF SYMPTOMATIC IRREVERSIBLE PULPITIS AND PERIAPICAL PERIODONTITIS: A RANDOMIZED CONTROL CLINICAL TRIAL
DOI:
https://doi.org/10.33279/jkcd.v3i1.512Keywords:
Postoperative pain, Antibiotics, Irreversible pulpitis, Periapical periodontitis.Abstract
Objective: To determine the role of antibiotics in post endodontic pain in cases of acute irreversible pulpitis and acute periapical periodontitis.
Material and Methods: This was a randomized controlled clinical trial of 90 subjects with symptomatic irreversible pulpitis and periapical periodontitis. This study was carried out at the department of Operative Dentistry, Khyber College of Dentistry, Peshawar, from August 2011 to December 2011. The subjects were divided into two groups, placebo and antibiotic group with 45 subjects in each group. Data was collected on the pain experienced using the visual analog scale (VAS) at 12, 24, 48 and 72 hours intervals respectively.
Results: Ninety subjects were included in this study with age range 10-63 years. Among these 52.2% were females and 47.8% were males. Postoperative pain was 64.4% and 66.7% in placebo and antibiotic group respectively in the first 12 hours and markedly reduced in the following 72 hours. Females were found to have experienced more pain in the first 12 hours than males (P<0.05).
Statistically no significant difference in occurrence of pain was found between various age groups (p>0.05).
Conclusion: This study concluded that antibiotics have no significant role in the control of post endodontic pain.
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Copyright (c) 2012 Khalid Rehman, Iftikhar Akber, Javed A Qazi

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