CHORIONIC VILLOUS SAMPLING TECHNIQUE; AWARENESS AMONG THE PARENTS OF THALASSEMIA CHILDREN AND ITS ROLE IN THE PREVENTION OF THALASSEMIA MAJOR
DOI:
https://doi.org/10.33279/jkcd.v9i04.389Keywords:
Chorionic villous sampling (CVS), β – thalassemia, Premarital screening, Sensitivity, and Specificity.Abstract
Objective: To determine the awareness level of parents of Thalassemia children regarding CVS technique and the role of this technique in the prevention of thalassemia.
Materials & Methods: It was a cross sectional study conducted in Frontier blood transfusion services Peshawar on 130 subjects selected through a convenient sampling technique within six months from Jan; 2018 to Jun; 2018. A questionnaire was used for the collection of data. Those women who had at least one Thalassemia major child were included while women unwilling or having children with other genetic disorders were excluded from the study. Data were analyzed using SPSS version 20.
Results: Of the total 130 women, only 50 underwent CVS. The sensitivity of the test was 75 % while specificity was 91 %. Of the total 76 % were cousin marriages while 24 % were non-cousin marriages. Of the total 101 mothers were aware while only 29 mothers were unaware of the technique. The main source of awareness was the physicians who referred them for the procedure.
Conclusion: The general public and parents of thalassemia children have limited knowledge about the prevention of thalassemia through the CVS technique. Diagnostic centers need to be established at the divisional level.
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Copyright (c) 2019 Hayat Muhammad Khan, Jehan Hussan, Saifoor Ahmed Khan, Natasha Junaid, Nighat Musa

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