HISTOPATHOLOGICAL PATTERN OF SQUAMOUS CELL CARCINOMA AT VARIOUS INTRAORAL SITES
DOI:
https://doi.org/10.33279/jkcd.v9i03.357Keywords:
Pattern, Squamous Cell Carcinoma, Intraoral site, AbbottabadAbstract
Objective: The objective of this study was to determine the histopathological pattern of OSCC and to assess any significant difference exist between the histopathological grading and pattern of OSCC at different intraoral sites in patients reported to the department of dentistry, Ayub Medical College and hospital, Abbottabad.
Materials and Methods: This cross-sectional study was conducted in the department of dentistry, Ayub Medical College and Hospital Abbottabad. The biopsy was obtained from 50 OSCC patients of primary tumor who reported between January 2017 to June 2019. A detailed history of snuff dipping, smoking, and tobacco chewing was taken and recorded in a proforma. The detailed intraoral and extraoral examination was carried out, and informed consent was obtained from the patients. The tongue mucosa, buccal mucosa, gingival mucosa, the floor of the mouth, palate, and oropharyngeal mucosa were included in the study. The site of Incisional or excisional biopsy for OSCC was selected by clinical examination and intravital staining with toluidine blue solution.
Results: The mean age was 47.14 ±9.82 years. 36(72%) were male, and 14(28%) were female. 31(62%) patients had a history of snuff dipping, 9(18%) patients were having the history of tobacco smoking, 7(14%) patients had a history of tobacco chewing, snuff dipping and smoking simultaneously, 3(6%) patients were having no history of smoking or snuff dipping.14(28%) Cases were well-differentiated, 27(54%) cases were moderately differentiated, and 9(18%) cases were poorly differentiated OSCC. 19(38%) cases occur on the lateral ventral surface of the tongue followed by 13(26%) buccal mucosa, 08(16%) floor of the mouth, 05(10%) palatal mucosa, 03(06%) gingival mucosa, and 02(04%) oropharynx.
Conclusion: OSCC was diagnosed between the 5th and sixth decade of life, and snuff dipping appeared to be a significant cause. Common in men and the tongue is the most common site. Poorly differentiated OSCC seen in people with a habit of snuff dipping and smoking. Several sections of the malignant tissue should be taken to exclude the possibility of any other variant of OSCC
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Copyright (c) 2019 Abdur Rehman, Shagufta Naeem, Sultan Zeb Khan, Khurshid Ali, Sadaf Waris, Syed Umar Farooq
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