EFFICACY OF PRETREATMENT WITH SINGLE DOSE PREDNISOLONE IN REDUCING POST-ENDODONTIC PAIN

Authors

  • Ambreen Khurshid Haider Lecturer Dentistry department, Ayub Medical College Abbottabad.
  • Nadia Munir Assistant Professor, Dentistry department, Ayub Medical College Abbottabad.
  • Saad Qureshi Armed Forces Institute of Dentistry, Rawalpindi.
  • Nofil Mushtaq Islamic International Medical College, Islamabad.
  • Ans Mushtaq Islamic International Medical College, Islamabad.

DOI:

https://doi.org/10.33279/jkcd.v8i01.456

Keywords:

Post endodontic pain, Prednisolone, Steroidal anti-inflammatory drugs, Pre-treatment

Abstract

Objective:To determine the efficacy of pretreatment with single dose prednisolone in reducing post-endodontic pain within 24 hours of the procedure.
Materials and Methods:This study was randomised Clinical Trial (RCT) comprising 110 patients of both genders reported to for non-surgical endodontic treatment over the period of six months. Patients were divided into two groups equally by blocked randomisation. Patients in group I was given placebo (dextrose capsule), and those in group II were given Prednisolone (30mg) orally 30 minutes before the procedure of root canal. Tablet was disguised in a manner that the patient was not aware of medication he was taking. Patients were then asked to mark their pain level experience on Visual Analogue Scale (VAS) both before treatment and 24hrs after endodontic treatment. All the findings were entered in the proforma. Data were analysed using SPSS version 20.
Results:Mean age of the total 110 patients of both groups was 48.85±9.95. Where 63 (57.3%) were male patients and 47(42.7%) were female patients. In group-I (Dextrose capsule) was no pain found in, 10 (18.2%), mild pain 20 (36.4%), moderate pain 15 (27.3%) and severe pain was found in 10 (18.2%) out of 55 patients. In group II (Prednisolone), no pain was found in 45(81.8%), mild pain 05(9.1%), moderate pain 05(9.1%) no one found with severe pain out of 55 patients.Pain intensity showed a statistically significant decline after 24 hours (P =0.001).
Conclusion:Pre-treatment with Prednisolone resulted in significant reduction in post-endodontic pain.

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Published

2018-03-31

How to Cite

Haider, A. K. ., Nadia Munir, Saad Qureshi, Nofil Mushtaq, & Ans Mushtaq. (2018). EFFICACY OF PRETREATMENT WITH SINGLE DOSE PREDNISOLONE IN REDUCING POST-ENDODONTIC PAIN . JOURNAL OF KHYBER COLLEGE OF DENTISTRY, 8(01), 14–18. https://doi.org/10.33279/jkcd.v8i01.456