THE ROLE OF HYPERBILIRUBINEMIA IN THE DIAGNOSIS OF COMPLICATED APPENDICITIS A CLINICAL SURVEY
DOI:
https://doi.org/10.33279/jkcd.v9i02.377Keywords:
Hyperbilirubinemia, complicated appendicitis, uncomplicated appendicitisAbstract
Objective: The aim of this study was to determine the serum total bilirubin level for preoperative diagnosis of complicated appendicitis.
Materials & Methods:
This study was prospective observational study conducted in emergency department of a private health care facility of Peshawar from May 2018 to Nov 2018. Patients with abdominal pain complaints who were admitted to Emergency departmentduring 6 month were included in the study based on the initial clinical examination for acute appendicitis. Data from each patient, including demographic data, duration of pain, symptoms, fever and history of liver disease and the results of initial examinations, were entered into a questionnaire. For all patients, complete white blood cell count and total serum bilirubin level were measured and the results were entered in the questionnaire.For those undergoing surgery, macroscopic findings and the pathology response of the sample were included in the questionnaire.Statistical analysis was carried out using SPSS version 21. Descriptive analyses were reported as mean of continuous variables. A value of P<0.005 was accepted as statistically significant.
Results:
Of the 295 patients studied, the most cases of appendicitis were between the ages of 15 to 24 years (42.7%) and the mean age was 30.35 years.Of these, 60% were males and 40% were females.Leukocytosis and left shift in cases of complicated appendicitis (98.5%) were significantly higher than those with uncomplicated appendicitis (85.6%) were.In addition, the study showed
that bilirubin level was significantly higher in complicated cases compared to uncomplicated group (P<0.0.1). In the present study, the association between the complications of appendicitis with bilirubin level was found to be higher in patients with clinical symptoms of appendicitis and hyperbilirubinemia compared with those with normal bilirubin levels.Therefore, the total
serum bilirubin level, as a test along with WBC, can be used to evaluate and diagnose cases of complicatedappendicitis.
Conclusion:
The total serum bilirubin level, as a test along with WBC, can be used to evaluate and diagnose cases of complicated appendicitis.
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Copyright (c) 2019 Shahid Nisar Khalid, Naeem Khattak, Anwar Khan Wazir, Salahuddin Zeb Khan, Wajiha Naeem
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