DISCRETION VALUES OF LIMBAL STEM CELL GRAFT WITH COMPARISON OF CONJUCTIVAL AUTOGRAFT IN PTERYGIUM EXCISION
DOI:
https://doi.org/10.33279/jkcd.v10i01.288Keywords:
Pterygium, limbal stem cell graft, conjunctival autograft, randomized clinical trial.Abstract
Objective: To determine the recurrence rate of pterygium in cases treated with limbal stem stem cell graft versus connjuctival autograft.
Materials and Methods: It was a randomized clinical trial conducted in Opthalmology department of Hayatabad Medical Complex Peshawar from January 2018 to February 2019 i.e one year study duration . A total of 60 diagnosed cases of pterygium of both sexes and all ages were included in the study . The cases were randomized into two groups i.e 30 cases were treated with stem cell graft while the other 30 cases were treated with conjunctival autograft .The recurrence rate of pterygium was determined in both the groups by following them for 6 months i.e at 1st , 3rd and 6th month of excision. Recurrence rate was calculated for both the procedures. Mean and standard deviations were used for quantitative variables while frequency and percentages were used for qualitative data.
Results: A total of 60 diagnosed cases of pterygium were included in the study. Age of the study sample ranged from 22-55 years, with mean of 37±9.3 SD. About 36 (60%) cases were males and ,14 (40%) cases were females. Recurrence rate of pterygium was 3.3% in cases treated with limbal stem cell graft technique as compared to recurrence rate of 10% which was seen in cases treated with conjunctival autograft technique.
Conclusion: Recurrence rate of pterygium was more in cases treated with conjunctival autograft as compared to those treated with limbal stem cell graft. So, limbal stem cell graft is more effective as compared to conjunctival autograft in treating pterygium and should be preferred treatment option for pterygium in order to decrease the recurrence rate and hence morbidity of the patient.
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Copyright (c) 2020 Hizbur Rahman, Tooba Rana, Samina Karim, Nosheen Kanwal, Barjis Irum

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