DIAGNOSTIC ACCURACY OF TYPHIDOT TEST IN PEDIATRIC PATIENTS PRESENTING WITH ENTERIC FEVER IN TERTIARY CARE HOSPITAL
DOI:
https://doi.org/10.33279/jkcd.v13i1.103Keywords:
Typhoid fever, blood culture, Typhidot test, diagnostic accuracy, sensitivity, specificityAbstract
Objectives: To determine the diagnostic accuracy of typhidot test against the gold standard blood culture in the children with enteric fever.
Materials and Methods: This Cross-sectional validation study was conducted on 111 children having age range of 2-16 years with documented fever of equal or greater than 380C for 1 week or more were included.All patients were evaluated for enteric fever by clinical signs & symptoms and laboratory investigations. Typhidot test, blood culture and sensitivity, full blood count, malarial parasite test, liver functional test, urine examination was done. The specifi city, Sensitivity, negative predictive value and positive predictive values along with diagnostic accuracy were calculated in SPSS v.22 and Medcalc software.
Results: The mean age was 8.02±3.357 years. Of total45(40.5%) were males while 66(59.5%) were female. There was no significant diff erence between typhidot and blood culture in diagnosis of enteric fever (p=0.877). The true positives were 50 (72.5%) and true negatives were 11(26.2%).The sensitivity of typhidot was 72.46% and specifi city was 26.19%. The diagnostic accuracy was 54.95%.
Conclusion: Overall specificity and sensitivity of typhidottest is low.
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Copyright (c) 2023 Amir Muhammad, Khwaja Kamran, Bakht Biland, Mian Sarfraz Gul, Shireen Anwar

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